Information Seeking Support System for E-Learning

[[abstract]]How to provide a multimedia information seeking support system (ISSS) is becoming more and more imperative. In this paper, we provide a multimedia ISSS for e-learning. This system requires flexible support for the modeling of multimedia content models and also supports possible interactivity, transfer of streams multimedia data such as audio, video, text and annotations using network facilities. However, we investigated the existing standards and applications for multimedia documents models such as HTML, MHEG, SMIL, and HyTime etc. We propose a new approach for the modeling of reusable and adaptable multimedia content. We also developed a comprehensive system for advanced multimedia content production: support for recording the presentation, retrieving the content, summarizing the presentation, weaving the presentation and customizing the representation. This approach significantly impacts and supports the multimedia presentation authoring processes in terms of methodology and commercial aspects.[[sponsorship]]IEEE Taipei Section; National Science Council; Ministry of Education; Tamkang University; Asia University; Providence University; The University of Aizu; Lanzhou University[[conferencetype]]國際[[conferencetkucampus]]淡水校園[[conferencedate]]20091203~20091205[[booktype]]紙本[[iscallforpapers]]Y[[conferencelocation]]Tamsui, Taipei, Taiwa

Universal Access for Roaming User via Mobile Agent Technology

[[abstract]]Mobile agents refer to self-contained and identifiable computer programs that can migrate along the network and can act on behalf of the user or other agents. Mobile agents often work on heterogeneous network and operating system environment. Therefore, an integrated logical interface to access physical structure via mobile agent application is become more and more urgent. In this paper, we proposed a tracking and persistent agent-based mobility management system in the case of distance learning. The main purpose of our system is addressed to achieve the universal access objective. In order to let the whole mobility management system full play, we encapsulated the utility tools to be a role-setting object. The role-setting object is an application-driven component, which can provide customization benefits for user and matching the user’s demands. These integrated technologies are sufficient in distance learning (virtual university) environment.[[notice]]補正完

The Physical Connections Among IR QSOs, PG QSOs and Narrow-Line Seyfert 1 Galaxies

We study the properties of infrared-selected QSOs (IR QSOs), optically-selected QSOs (PG QSOs) and Narrow Line Seyfert 1 galaxies (NLS1s). We compare their properties from the infrared to the optical and examine various correlations among the black hole mass, accretion rate, star formation rate and optical and infrared luminosities. We find that the infrared excess in IR QSOs is mostly in the far infrared, and their infrared spectral indices suggest that the excess emission is from low temperature dust heated by starbursts rather than AGNs. The infrared excess is therefore a useful criterion to separate the relative contributions of starbursts and AGNs. We further find a tight correlation between the star formation rate and the accretion rate of central AGNs for IR QSOs. The ratio of the star formation rate and the accretion rate is about several hundred for IR QSOs, but decreases with the central black hole mass. This shows that the tight correlation between the stellar mass and the central black hole mass is preserved in massive starbursts during violent mergers. We suggest that the higher Eddington ratios of NLS1s and IR QSOs imply that they are in the early stage of evolution toward classical Seyfert 1's and QSOs, respectively.Comment: 32 pages, 6 figures, accepted by Ap

Spectroscopic Properties of QSOs Selected from Ultraluminous Infrared Galaxy Samples

We performed spectroscopic observations for a large infrared QSO sample with a total of 25 objects. The sample was compiled from the QDOT redshift survey, the 1 Jy ULIRGs survey and a sample obtained by a cross-correlation study of the IRAS Point Source Catalogue with the ROSAT All Sky Survey Catalogue. Statistical analyses of the optical spectra show that the vast majority of infrared QSOs have narrow permitted emission lines (with FWHM of Hbeta less than 4000 km/s) and more than 60% of them are luminous narrow line Seyfert 1 galaxies. Two of the infrared QSOs are also classified as low ionization BAL QSOs. More than 70% of infrared QSOs are moderately or extremely strong Fe II emitters. This is the highest percentage of strong Fe II emitters in all subclasses of QSO/Seyfert 1 samples. We found that the Fe II to Hbeta, line ratio is significantly correlated with the [OIII]5007 peak and Hbeta blueshift. Soft X-ray weak infrared QSOs tend to have large blueshifts in permitted emission lines and significant Fe II48,49 (5100--5400 A) residuals relative to the Boroson & Green Fe II template. If the blueshifts in permitted lines are caused by outflows, then they appear to be common in infrared QSOs. As the infrared-selected QSO sample includes both luminous narrow line Seyfert 1 galaxies and low ionization BAL QSOs, it could be a useful laboratory to investigate the evolutionary connection among these objects.Comment: 35 pages,14 figures, 4 tables, accepted for publication in A

Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation

BACKGROUND: Maternal immune activation (MIA) during prenatal life is a risk factor for neurodevelopmental disorders including schizophrenia and autism. Such conditions are associated with alterations in fronto-subcortical circuits, but their molecular basis is far from clear. METHODOLOGY/PRINCIPAL FINDINGS: Using two-dimensional differential in-gel electrophoresis (2D-DIGE) and mass spectrometry, with targeted western blot analyses for confirmation, we investigated the impact of MIA on the prefrontal and striatal proteome from an established MIA mouse model generated in C57B6 mice, by administering the viral analogue PolyI:C or saline vehicle (control) intravenously on gestation day (GD) 9. In striatum, 11 proteins were up-regulated and 4 proteins were down-regulated in the PolyI:C mice, while 10 proteins were up-regulated and 7 proteins down-regulated in prefrontal cortex (PFC). These were proteins involved in the mitogen-activated protein kinase (MAPK) signaling pathway, oxidation and auto-immune targets, including dual specificity mitogen-activated protein kinase kinase 1 (MEK), eukaryotic initiation factor (eIF) 4A-II, creatine kinase (CK)-B, L-lactate dehydrogenase (LDH)-B, WD repeat-containing protein and NADH dehydrogenase in the striatum; and guanine nucleotide-binding protein (G-protein), 14-3-3 protein, alpha-enolase, olfactory maker protein and heat shock proteins (HSP) 60, and 90-beta in the PFC. CONCLUSIONS/SIGNIFICANCE: This data fits with emerging evidence for disruption of critical converging intracellular pathways involving MAPK pathways in neurodevelopmental conditions and it shows considerable overlap with protein pathways identified by genetic modeling and clinical post-mortem studies. This has implications for understanding causality and may offer potential biomarkers and novel treatment targets for neurodevelopmental conditions

Forecasting Player Behavioral Data and Simulating in-Game Events

Understanding player behavior is fundamental in game data science. Video games evolve as players interact with the game, so being able to foresee player experience would help to ensure a successful game development. In particular, game developers need to evaluate beforehand the impact of in-game events. Simulation optimization of these events is crucial to increase player engagement and maximize monetization. We present an experimental analysis of several methods to forecast game-related variables, with two main aims: to obtain accurate predictions of in-app purchases and playtime in an operational production environment, and to perform simulations of in-game events in order to maximize sales and playtime. Our ultimate purpose is to take a step towards the data-driven development of games. The results suggest that, even though the performance of traditional approaches such as ARIMA is still better, the outcomes of state-of-the-art techniques like deep learning are promising. Deep learning comes up as a well-suited general model that could be used to forecast a variety of time series with different dynamic behaviors

Mid-Infrared Spectroscopic Properties of Ultra-Luminous Infrared Quasars

We analyse mid-infrared (MIR) spectroscopic properties for 19 ultra-luminous infrared quasars (IR QSOs) in the local universe based on the spectra from the Infrared Spectrograph on board the Spitzer Space Telescope. The MIR properties of IR QSOs are compared with those of optically-selected Palomar-Green QSOs (PG QSOs) and ultra-luminous infrared galaxies (ULIRGs). The average MIR spectral features from ~ 5 to 30um, including the spectral slopes, 6.2um PAH emission strengths and [NeII] 12.81um luminosities of IR QSOs, differ from those of PG QSOs. In contrast, IR QSOs and ULIRGs have comparable PAH and [NeII] luminosities. These results are consistent with IR QSOs being at a transitional stage from ULIRGs to classical QSOs. We also find that the colour index alpha(30, 15) is a good indicator of the relative contribution of starbursts to AGNs for all QSOs. Correlations between the [NeII] 12.81um and PAH 6.2um luminosities and those between the [NeII], PAH with 60um luminosities for ULIRGs and IR QSOs indicate that both [NeII] and PAH luminosities are approximate star formation rate indicators for IR QSOs and starburst-dominated galaxies; the scatters are, however, quite large (~ 0.7 to 0.8 dex). Finally the correlation between the EW(PAH 6.2um) and outflow velocities suggests that star formation activities are suppressed by feedback from AGNs and/or supernovae.Comment: 19 pages, 8 figures, 6 tables, accepted for publication in MNRA

A Catalog of Luminous Infrared Galaxies in the IRAS Survey and the Second Data Release of the SDSS

We select the Luminous Infrared Galaxies by cross-correlating the Faint Source Catalogue (FSC) and Point Source Catalogue (PSC) of the IRAS Survey with the Second Data Release of the SDSS for studying their infrared and optical properties. The total number of our sample is 1267 for FSC and 427 for PSC by using 2$\sigma$ significance level cross-section. The "likelihood ratio" method is used to estimate the sample's reliability and for a more reliable subsample (908 for FSC and 356 for PSC) selection. Then a Catalog with both the infrared, optical and radio informations is presented and will be used in further works. Some statistical results show that the Luminous Infrared Galaxies are quite different from the Ultra-Luminous Infrared Galaxies. The AGN fractions of galaxies with different infrared luminosities and the radio to infrared correlations are consist with previous studies.Comment: 15 pages, 11 figures. Accepted by ChJAA. Reference adde

Sperm Chromatin-Induced Ectopic Polar Body Extrusion in Mouse Eggs after ICSI and Delayed Egg Activation

Meiotic chromosomes in an oocyte are not only a maternal genome carrier but also provide a positional signal to induce cortical polarization and define asymmetric meiotic division of the oocyte, resulting in polar body extrusion and haploidization of the maternal genome. The meiotic chromosomes play dual function in determination of meiosis: 1) organizing a bipolar spindle formation and 2) inducing cortical polarization and assembly of a distinct cortical cytoskeleton structure in the overlying cortex for polar body extrusion. At fertilization, a sperm brings exogenous paternal chromatin into the egg, which induces ectopic cortical polarization at the sperm entry site and leads to a cone formation, known as fertilization cone. Here we show that the sperm chromatin-induced fertilization cone formation is an abortive polar body extrusion due to lack of spindle induction by the sperm chromatin during fertilization. If experimentally manipulating the fertilization process to allow sperm chromatin to induce both cortical polarization and spindle formation, the fertilization cone can be converted into polar body extrusion. This suggests that sperm chromatin is also able to induce polar body extrusion, like its maternal counterpart. The usually observed cone formation instead of ectopic polar body extrusion induced by sperm chromatin during fertilization is due to special sperm chromatin compaction which restrains it from rapid spindle induction and therefore provides a protective mechanism to prevent a possible paternal genome loss during ectopic polar body extrusion

Distinct Mechanisms for Induction and Tolerance Regulate the Immediate Early Genes Encoding Interleukin 1β and Tumor Necrosis Factor α

Interleukin-1β and Tumor Necrosis Factor α play related, but distinct, roles in immunity and disease. Our study revealed major mechanistic distinctions in the Toll-like receptor (TLR) signaling-dependent induction for the rapidly expressed genes (IL1B and TNF) coding for these two cytokines. Prior to induction, TNF exhibited pre-bound TATA Binding Protein (TBP) and paused RNA Polymerase II (Pol II), hallmarks of poised immediate-early (IE) genes. In contrast, unstimulated IL1B displayed very low levels of both TBP and paused Pol II, requiring the lineage-specific Spi-1/PU.1 (Spi1) transcription factor as an anchor for induction-dependent interaction with two TLR-activated transcription factors, C/EBPβ and NF-κB. Activation and DNA binding of these two pre-expressed factors resulted in de novo recruitment of TBP and Pol II to IL1B in concert with a permissive state for elongation mediated by the recruitment of elongation factor P-TEFb. This Spi1-dependent mechanism for IL1B transcription, which is unique for a rapidly-induced/poised IE gene, was more dependent upon P-TEFb than was the case for the TNF gene. Furthermore, the dependence on phosphoinositide 3-kinase for P-TEFb recruitment to IL1B paralleled a greater sensitivity to the metabolic state of the cell and a lower sensitivity to the phenomenon of endotoxin tolerance than was evident for TNF. Such differences in induction mechanisms argue against the prevailing paradigm that all IE genes possess paused Pol II and may further delineate the specific roles played by each of these rapidly expressed immune modulators. © 2013 Adamik et al